Two ways of preparing benzonitriles using BrCCl3-PPh3 as the reagent

Yosef Al Jasem, Mohamed Barkhad, Mona Al Khazali, Hifsa Pervez Butt, Noha Ashraf El-Khwass, Mariam Al Azani, Bassam Al Hindawi, Thies Thiemann

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Benzamides were converted into benzonitriles with BrCCl3- PPh3-Et3N in CH2Cl2 in an Appel-type reaction. Benzaldoximes could be transformed to benzonitriles under identical conditions. It was found that the reaction system BrCCl3-(2 equiv.)PPh3 was also suitable for these transformations with PPh 3 replacing Et3N.

Original languageEnglish
Pages (from-to)80-84
Number of pages5
JournalJournal of Chemical Research
Volume38
Issue number2
DOIs
Publication statusPublished - Feb 2014

Keywords

  • Appel-type reaction
  • Benzaldoximes
  • Benzamides
  • Benzonitriles
  • Bromotrichloromethane

ASJC Scopus subject areas

  • Chemistry(all)

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