Synthesis, spectral studies and biological evaluation of 2-aminonicotinic acid metal complexes

Muhammad Nawaz, Muhammad Waseem Abbasi, Soleiman Hisaindee, Muhammad Javed Zaki, Hira Fatima Abbas, Hu Mengting, M. Arif Ahmed

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

We synthesized 2-aminonicotinic acid (2-ANA) complexes with metals such as Co(II), Fe(III), Ni(II), Mn(II), Zn(II), Ag(I),Cr(III), Cd(II) and Cu(II) in aqueous media. The complexes were characterized and elucidated using FT-IR, UV-Vis, a fluorescence spectrophotometer and thermo gravimetric analysis (TGA). TGA data showed that the stoichiometry of complexes was 1:2 metal/ligand except for Ag(I) and Mn(II) where the ratio was 1:1. The metal complexes showed varied antibacterial, fungicidal and nematicidal activities. The silver and zinc complexes showed highest activity against Bacillus subtilis and Bacillus licheniformis respectively. Fusarium oxysporum was highly susceptible to nickel and copper complexes whereas Macrophomina phaseolina was completely inert to the complexes. The silver and cadmium complexes were effective against the root-knot nematode Meloidogyne javanica.

Original languageEnglish
Pages (from-to)39-43
Number of pages5
JournalSpectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume161
DOIs
Publication statusPublished - May 15 2016

Keywords

  • 2-Aminonicotinic acid
  • Biological activity
  • Metal complexes
  • Spectral studies

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics
  • Analytical Chemistry
  • Spectroscopy

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