We found in the Ca2+ channel α(1C) subunit gene a new repetitive element of three paired exon 45/46-related sequences. We also identified a new exon 45/46-related sequence in the human genome and mapped it by fluorescence in situ hybridization to the 12p11.2 and 12p13.2-p13.1 bands. These positions are not recognized by DNA probes generated from the 5'- and 3'-terminal regions of the α(1C) gene. A possible existence of a new genomic homologue of the α(1C) subunit gene is discussed.
- Calcium channel gene
- Chromosome mapping
- Fluorescence in situ hybridization
- Repetitive sequences
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