Polymeric nanobiocomposites for biomedical applications

Research output: Contribution to journalReview articlepeer-review

28 Citations (Scopus)

Abstract

Polymeric nanobiocomposites have recently become one of the most essential sought after materials for biomedical applications ranging from implants to the creation of gels. Their unique mechanical and biological properties provide them the ability to pass through the highly guarded defense mechanism without undergoing noticeable degradation and initiation of immune responses, which in turn makes them advantageous over the other alternatives. Aligned with the advances in tissue engineering, it is also possible to design three-dimensional extracellular matrix using these polymeric nanobiocomposites that could closely mimic the human tissues. In fact, unique polymer chemistry coupled with nanoparticles could create unique microenvironment that promotes cell growth and differentiation. In addition, the nanobiocomposites can also be devised to carry drugs efficiently to the target site without exhibiting any cytotoxicity as well as to eradicate surgical infections. In this article, an effort has been made to thoroughly review a number of different types/classes of polymeric nanocomposites currently used in biomedical fields.

Original languageEnglish
Pages (from-to)1241-1259
Number of pages19
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume105
Issue number5
DOIs
Publication statusPublished - Jul 2017

Keywords

  • biological properties
  • mechanical properties
  • nanobiocomposites
  • polymer
  • scaffolds
  • tissue engineering

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

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