Plasma motilin, gastrin, and enteroglucagon and feeding in the human newborn

A. Lucas, T. E. Adrian, N. Christofides, S. R. Bloom, A. Aynsley-Green

Research output: Contribution to journalArticlepeer-review

73 Citations (Scopus)

Abstract

Plasma concentrations of motilin, gastrin, and enteroglucagon were measured in cord blood and during the first 24 days of life before feeding in 45 term and 63 preterm, healthy infants. Levels of these hormones rose steeply after birth, reaching concentrations that were much higher than those in fasting adults. These increases in hormone concentration were not present in a group of 10 preterm infants who had received only intravenous dextrose from birth because of hyaline membrane disease. Our findings suggest that early enteral feeding may trigger the postnatal increase in plasma concentrations of gut hormones and that this could play an important role in the physiological adaptations to extrauterine nutrition.

Original languageEnglish
Pages (from-to)673-677
Number of pages5
JournalArchives of Disease in Childhood
Volume55
Issue number9
DOIs
Publication statusPublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint

Dive into the research topics of 'Plasma motilin, gastrin, and enteroglucagon and feeding in the human newborn'. Together they form a unique fingerprint.

Cite this