Novel finding of high density of activated mast cells in endometrial polyps

Moamar Al-Jefout, Kirsten Black, Lauren Schulke, Marina Berbic, Georgina Luscombe, Natsuko Tokushige, Frank Manconi, Robert Markham, Ian S. Fraser

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compared with normal endometrium. This novel finding has important implications for growth, development, and symptoms associated with polyps in many different tissues.

Original languageEnglish
Pages (from-to)1104-1106
Number of pages3
JournalFertility and Sterility
Volume92
Issue number3
DOIs
Publication statusPublished - Sep 2009
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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