New platinum and ruthenium complexes - The latest class of potential chemotherapeutic drugs - A review of recent developments in the field

Amr Amin, Michael A. Buratovich

Research output: Contribution to journalShort surveypeer-review

41 Citations (Scopus)

Abstract

New Platinum and Ruthenium complexes display antitumour and antimetastatic potentials and lower host toxicities. This mini-review examines some the more recent developments in this field, and explores their interactions with biologically-relevant species. The article also refers to more recent work in the area of molybdenum and copper(II) chemistry.

Original languageEnglish
Pages (from-to)1489-1503
Number of pages15
JournalMini-Reviews in Medicinal Chemistry
Volume9
Issue number13
DOIs
Publication statusPublished - Nov 2009

Keywords

  • Apoptosis
  • BBR3464
  • Cancer
  • Chemotherapeutics
  • Cisplatin
  • KP1019
  • Lipoplatin
  • NAMI-A
  • Picoplatin
  • RAPTA
  • Satraplatin

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Cancer Research

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