Neuropsychological and activity of daily living script performance in patients with positive or negative schizophrenia

Lucie Godbout, Frédérique Limoges, Isabelle Allard, Claude M.J. Braun, Emmanuel Stip

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Cognitive and psychiatric determinants of impairment of complex activities of daily living (ADLs) were investigated in 33 schizophrenic patients and 16 normal comparison subjects. The schizophrenic patients were cognitively impaired and were deficient in the ADL. However, the impairment of ADL could not be explained specifically by impairment of higher-order executive function or by negative symptoms: memory functions were more related to impairment of ADL and positive symptoms as much as the negative ones. Positive symptoms were significantly related to commissive errors in the ADL, whereas negative symptoms were nonsignificantly related to omissive errors. Negative symptoms were significantly more related to memory impairment than to impairment on measures of higher-order executive function (working memory). This investigation demonstrates that an ecologically oriented approach to test development and measurement of ADL is fruitful in understanding schizophrenia-especially if it is constrained by cognitive constructs compatible with the phenomenology of the disease.

Original languageEnglish
Pages (from-to)293-302
Number of pages10
JournalComprehensive Psychiatry
Volume48
Issue number3
DOIs
Publication statusPublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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