The association between ABO and Rh blood groups and the incidence of various types of cancers has been previously investigated, but with no definite consensus reached. Since lung cancer has become one of the most leading causes of cancer-related deaths, its relation to ABO/Rh is being investigated in many centers. To explore the relationship between ABO and Rh blood groups and the risk of lung cancer. A case control study was conducted to explore the relationship between blood groups/Rh factor and the risk of lung cancer. Lung cancer cases (n=458) were identified from two major university hospitals. Control subjects included a total of 3,847 patients in which none is a cancer patient. ABO and Rh blood groups were typed and compared between cases and controls. The adjusted effect of Rh, but not ABO blood group, was significantly associated with the risk of lung cancer. The results of this study showed that Rh positive subjects are more likely to have lung cancer than the Rh negative subjects, indicating an association between Rh positivity and the risk of lung cancer. The Rh factor showed a significant association with lung cancer, but not with ABO blood groups. Further studies are needed to investigate this association to determine the role of Rh in the development of lung cancer.
|Number of pages||4|
|Journal||Jordan Journal of Biological Sciences|
|Publication status||Published - 2018|
- Blood group
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)