In vitro investigation of anticancer and ACE-inhibiting activity, α-amylase and α-glucosidase inhibition, and antioxidant activity of camel milk fermented with camel milk probiotic: A comparative study with fermented bovine milk

Mutamed Ayyash, Amna K. Al-Nuaimi, Suheir Al-Mahadin, Shao Quan Liu

    Research output: Contribution to journalArticlepeer-review

    103 Citations (Scopus)

    Abstract

    This study aimed to investigate in vitro the health-promoting benefits (anticancer activity, α-amylase and α-glucosidase inhibition, angiotensin-converting-enzyme (ACE)-inhibition, antioxidant and proteolytic activity) of camel milk fermented with indigenous probiotic strains of Lactobacillus spp., compared with fermented bovine milk. The three camel milk probiotic strains Lb. reuteri-KX881777, Lb. plantarum-KX881772, Lb. plantarum-KX881779 and a control strain Lb. plantarum DSM2468 were employed to ferment camel and bovine milks separately. The proteolytic and antioxidant activity of water soluble extracts (WSEs) from all fermented camel milks were higher than those of fermented bovine milk. α-Amylase inhibition of WSEs were >34% in both milk types fermented with all strains during storage periods, except the WSE of camel milk fermented by Lp.K772. The highest ACE-inhibition of the WSE from camel milk fermented by Lr.K777 was >80%. The proliferations of Caco-2, MCF-7 and HELA cells were more inhibited when treated with the WSE of fermented camel milk.

    Original languageEnglish
    Pages (from-to)588-597
    Number of pages10
    JournalFood Chemistry
    Volume239
    DOIs
    Publication statusPublished - Jan 15 2018

    Keywords

    • ACE-inhibition
    • Anticancer
    • Camel milk
    • Fermented
    • Probiotics

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Food Science

    Fingerprint

    Dive into the research topics of 'In vitro investigation of anticancer and ACE-inhibiting activity, α-amylase and α-glucosidase inhibition, and antioxidant activity of camel milk fermented with camel milk probiotic: A comparative study with fermented bovine milk'. Together they form a unique fingerprint.

    Cite this