High prevalence of ST-78 infection-associated vancomycin-resistant Enterococcus faecium from hospitals in Asunción, Paraguay

M. A. Khan, J. B. Northwood, R. G.J. Loor, A. T.R. Tholen, E. Riera, M. Falcón, A. van Belkum, M. van Westreenen, J. P. Hays

Research output: Contribution to journalComment/debatepeer-review

20 Citations (Scopus)

Abstract

Forty infection-associated VanA-type vancomycin-resistant Enterococcus faecium (VRE) strains obtained from five collaborating hospitals in Asunción, Paraguay were investigated. Genotyping using pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing revealed the presence of 17 cluster types and four STs, with 93% (37/40) of isolates comprising ST type 78. Other ST types included ST-132, ST-210 and one new ST type (ST-438). All but one isolate (ST-438) were associated with clonal complex 17 (CC17), and 97% of the total isolates carried the esp gene. Three Tn. 1546 variants were found, including a new lineage containing an IS. Efa5 insertion in an existing IS1251 element.

Original languageEnglish
Pages (from-to)624-627
Number of pages4
JournalClinical Microbiology and Infection
Volume16
Issue number6
DOIs
Publication statusPublished - Jun 2010
Externally publishedYes

Keywords

  • Bacterial genotypes
  • Insertion sequences
  • Multilocus sequence typing
  • Transposons
  • Vancomycin-resistant Enterococci

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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