Estrano[17,16-e]pyrimidine-amino acid and estrano[17,16-e]pyrimidinepeptide conjugates

Tomohiro Matsumoto, Kodai Shiine, Shuntaro Mataka, Thies Thiemanna

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Estrone has been converted to an aminopyrimidino [17,16-e]-annelated estrane derivative. A number of amino acids dipeptides and tripeptides have been linked to the aminopyrimidino unit of the annelated steroid. The tripeptide motifs may be used for the complexation of metals, such as of technetium as a radio label for the potential detection of estrogen positive breast cancer cells.

Original languageEnglish
Pages (from-to)391-396
Number of pages6
JournalJournal of Chemical Research
Issue number6
DOIs
Publication statusPublished - Jun 2009

Keywords

  • Breast cancer
  • Diagnostic agents
  • Estranes
  • Steroids

ASJC Scopus subject areas

  • Chemistry(all)

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