Engineering glucosinolates in plants: Current knowledge and potential uses

Venkidasamy Baskar, Mayank Anand Gururani, Jae Woong Yu, Se Won Park

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

Glucosinolates (GSL) and their derivatives are well known for the characteristic roles they play in plant defense as signaling molecules and as bioactive compounds for human health. More than 130 GSLs have been reported so far, and most of them belong to the Brassicaceae family. Several enzymes and transcription factors involved in the GSL biosynthesis have been studied in the model plant, Arabidopsis, and in a few other Brassica crop species. Recent studies in GSL research have defined the regulation, distribution, and degradation of GSL biosynthetic pathways; however, the underlying mechanism behind transportation of GSLs in plants is still largely unknown. This review highlights the recent advances in the metabolic engineering of GSLs in plants and discusses their potential applications.

Original languageEnglish
Pages (from-to)1694-1717
Number of pages24
JournalApplied Biochemistry and Biotechnology
Volume168
Issue number6
DOIs
Publication statusPublished - Nov 2012
Externally publishedYes

Keywords

  • Brassicaceae
  • Glucosinolate
  • Myrosinase
  • Transgenic

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology

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