Dielectrophoresis based cell switching in continuous flow microfluidic devices

Bobby Mathew, Anas Alazzam, Ghulam Destgeer, Hyung J. Sung

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

This article presents a novel negative-dielectrophoresis based approach for switching of a focused stream of micro-sized particles, including cells, to desired locations inside a continuous flow microfluidic device. The first section, of the device, focuses the incoming stream of micro-sized particles while the second section switches this focused stream of micro-sized particles. The microfluidic device consists of a glass substrate and a PDMS layer. The microfluidic device is realized using standard microfabrication. Tests are carried out using blood cells to demonstrate the efficacy of the approach in switching a stream of micro-sized particles to multiple locations inside the microchannel.

Original languageEnglish
Pages (from-to)63-72
Number of pages10
JournalJournal of Electrostatics
Volume84
DOIs
Publication statusPublished - Dec 1 2016
Externally publishedYes

Keywords

  • Cells
  • Dielectrophoresis
  • Micro-sized particles
  • Microchannel
  • Microfluidics
  • Switching

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biotechnology
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Electrical and Electronic Engineering

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