Comparison of erythrocyte indices to differentiate between iron deficiency and alpha-thalassaemias in children with microcytosis and/or hypochromia.

H. Narchi, R. B. Basak

Research output: Contribution to journalArticlepeer-review

Abstract

Erythrocyte indices used to differentiate between iron deficiency anaemia (IDA) and thalassaemias have been studied mainly in countries with a high prevalence of IDA or beta-thalassaemias. This study was carried out in the United Arab Emirates where alpha-thalassaemias are prevalent. We studied the predictive value and Youden index of several indices in 85 children aged 6 months to 12 years with microcytosis and/or hypochromia, with or without anaemia (determined by serum measurement of iron or therapeutic iron trial). The best discriminatory indices for detecting IDA versus alpha-thalassaemias were a Green-King index > 65 (correctly identified 75.3% of children, Youden index 44.3) and red cell distribution width >14% (correctly identified 57.8%, Youden index 38.1).

Original languageEnglish
Pages (from-to)966-971
Number of pages6
JournalEastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ihhīyah li-sharq al-mutawassi
Volume16
Issue number9
Publication statusPublished - Sep 2010

ASJC Scopus subject areas

  • Medicine(all)

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