Altered responsiveness of isolated arteries from pre-eclamptic subjects

A. B. Ebeigbe, M. Ezimokhai, C. P. Aloamaka

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The aetiology and pathology of pre-eclampsia, a hypertensive disorder peculiar to human pregnancy, is ill-defined. Numerous studies have reported that various forms of clinical and experimental hypertension as well as pre-eclamptic conditions are associated with increased peripheral vascular resistance (1-5), although the underlying mechanism is not clear. The present study presents evidence showing that the increased peripheral vascular resistance in pre-eclampsia is associated with direct functional changes within the vascular smooth muscle cell.

Original languageEnglish
Pages (from-to)381-382
Number of pages2
JournalIRCS Medical Science
Volume13
Issue number4
Publication statusPublished - Jan 1 1985

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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